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Certain antidepressants and topical anesthetic creams help treat premature ejaculation. Although none of these drugs are specifically approved to treat premature ejaculation by the Food and Drug Administration, many doctors prescribe these drugs because there is no specific drug available. Certain antidepressants can delay an orgasm. Doctors often suggest men who have premature ejaculation take antidepressants, often prescribing one of several selective, serotonin reuptake inhibitors (SSRIs), such as Sertraline, Paroxetine, or Fluoxetine to help delay ejaculation. If the timing of your ejaculation doesn't improve, your doctor may prescribe a stronger dosage of the tricyclic antidepressant, Clomipramine, which also has been shown to be effective for men with this disorder. Like many prescription drugs, there is a price to pay when using them. Side effects of these antidepressants can include nausea, dry mouth, drowsiness, decreased libido, weak erection, penis shrinkage, and termination of seminal production. [1] [2] [3]A natural approach to overcome premature ejaculation is a much safer and effective solution. Techniques such as Taoist's Natural Ejaculation Control Technique and Nerve Calming & Repair Solution For Premature Ejaculation have no side effects. Since both are techniques and not drugs, you will not see instant effects or any harmful side effect. Be patient. Spend time to learn them, and you will achieve better control over your ejaculation.